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刘昭飞

Zhaofei (Jeff) Liu, PhD, Associate Professor

E-mail:liuzf@bjmu.edu.cn

Tel:86-10-8280 2871

Fax:86-10-8280 1145

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EDUCATION
2004. B.M., Medical College of Qingdao University, China
2008-2009. Ph.D. Joint-Training Program, Stanford University, US
2009. Ph.D., Peking University, Beijing, China                 

AWARDS AND HONORS
2006 Medicine Award---Peking University
2007 Joint-Training Scholarship---China Scholarship Council (CSC)
2008 Berson-Yalow Award---Society of Nuclear Medicine (SNM)
2008 Travel Award---The 55th SNM Annual Meeting (New Orleans, US)
2009 Travel Award---The 56th SNM Annual Meeting (Toronto, Canada)
2010 EANM Springer Prize-2009 Best Basic Science Paper---European Association of Nuclear Medicine

 PROFESSIONAL ACTIVITIES
JOURNAL REVIEW:
Eur J Nucl Med Mol Imaging; Cur Pharm Biotechnol; J Med Chem; Curr Cancer Drug Targets; Bioorgan Med Chem; Int J Mol Imaging; Int J Nanomed; Med Chem; Nucl Sci Techn

TEACHING AND STUDENT SUPERVISION:
Undergraduate and graduate students of Peking University

 SELECTED PUBLICATIONS (* Equal contribution; # Corresponding author)
(Find Dr. Liu’s publications on PubMed, click http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=DetailsSearch&term=zhaofei+liu&log$=activity)


1.Liu Z, Shi J, Jia B, Yu Z, Liu Y, Zhao H, Li F, Tian J, Chen X, Liu S, Wang F. 90Y-labeled two multimeric RGD peptides RGD4 and 3PRGD2 for integrin targeted radionuclide therapy. Mol Pharm. 2011, 8:591-599. 

2.Liu Z*, Wang F, Chen X. Integrin targeted delivery of radiotherapeutics. Theranostics. 2011, 1:201-210.

3.Liu Z, Jia B, Zhao H, Chen X, Wang F. Specific targeting of human integrin αvβ3 with 111In-labeled AbegrinTM in nude mouse models. Mol Imaging Biol. 2011, 13:112-120. 

4.Liu Z, Wang F, Tian J. Molecular imaging is speeding up drug development. Asian J Pharmacokinet Pharmacodyn. 2010, 10:165-171.

5.Liu Z, Liu Y, Jia B, Zhao H, Chen X, Wang F. EGFR-targeted radioimmunotherapy of human head and neck cancer xenografts using 90Y-labeled panitumumab. Mol Cancer Ther. 2010, 9:2297-2308.

6.Liu Z*, Wang F. Dual-targeted molecular probes for cancer imaging. Curr Pharm Biotechnol. 2010, 11:610-9.

7Liu Z, Jin C, Yu Z, Yang Z, Liu Y, Zhao H, Jia B, Wang F. Radioimmunotherapy of human colon cancer xenografts with 131I-labeled anti-CEA monoclonal antibody. Bioconjugate Chem. 2010, 21:314-318.

8.Liu Z, Liu S, Niu G, Wang F, Liu S, Chen X. Optical imaging of integrin αvβ3 expression with near-infrared fluorescent RGD dimer with the tetra(ethylene glycol) linkers. Mol Imaging. 2010, 9:21-29.

9.Liu Z, Jia B, Shi J, Zhao H, Liu S, Wang F. Tumor uptake of the RGD dimeric probe 99mTc-G3-2P4-RGD2 is correlated with integrin αvβ3 expressed on both tumor cells and neovasculature. Bioconjugate Chem. 2010, 21: 548-555.

10.Zhao H, Jia B, Wang F, Liu Z*. Tumor targeting of 125I-labeled anti-EGFR monoclonal antibody LA22 in HT-29 human colon cancer.  Nucl Sci Techn. 2010, 21: 84-88.

11.Liu Z, Yu Z, He W, Ma S, Sun L, Wang F. In vitro internalization and in vivo tumor uptake of anti-EGFR monoclonal antibody LA22 in A549 lung cancer cells and animal model. Cancer Biother Radiopharm. 2009, 24:15-23.

12.Liu Z, Niu G, Shi J, Liu S, Wang F, Liu S, Chen X. 68Ga-labeled cyclic RGD dimers with Gly3 and PEG4 linkers: promising agents for tumor integrin αvβ3 PET imaging. Eur J Nucl Med Mol Imaging. 2009, 36:947-957.

13.Liu Z, Yan Y, Chin FT. Wang F, Chen X. Dual integrin and gastrin-releasing peptide receptor targeted tumor imaging using 18F-labeled PEGylated RGD-bombesin heterodimer 18F-FB-PEG3-Glu-RGD-BBN. J Med Chem. 2009, 52:425-32.

14.Liu Z, Liu S, Wang F, Liu S, Chen X. Non-invasive imaging of tumor integrin expression using 18F-labeled RGD dimer peptide with PEG4 linkers. Eur J Nucl Med Mol Imaging. 2009, 36:1296-307.

15.Liu Z, Li Z, Cao Q, Liu S, Wang F, Chen X. Small animal PET of tumors with 64Cu-labeled RGD-bombesin heterodimer. J Nucl Med. 2009, 50: 1168-1177.

16.Liu Z, Niu G, Wang F, Chen X. 68Ga-labeled-NOTA-RGD-BBN for dual integrin and GRPR targeted tumor imaging in nude mice model. Eur J Nucl Med Mol Imaging. 2009, 36:1483-94.

17.Liu Z, Yan Y, Liu S, Wang F, Chen X. 18F, 64Cu, and 68Ga labeled RGD-bombesin heterodimeric peptides for PET imaging of breast cancer. Bioconjugate Chem, 2009, 20: 1016-1025.

18.Liu Z, Wang F, Chen X. Integrin αvβ3 targeted cancer therapy. Drug Develop Res. 2008, 69: 329-339.

中心地址:北京市海淀区学院路38号  电话:010-82802871  传真:010-82801145    邮编:100191
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